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Article

B23/nucleophosmin serine 4 phosphorylation mediates mitotic functions of polo-like kinase 1.

The Journal of biological chemistry - 20 Aug 2004

Zhang Hong, Shi Xiaoqing, Paddon Harry, Hampong Maggie, Dai Wei, Pelech Steven

Abstract excerpt

Phosphoprotein profiling by Kinetworks trade mark analysis of M-phase-arrested HeLa cells by nocodazole treatment revealed that a novel mitosis-specific phosphorylation event occurred in the nucleolar protein B23/nucleophosmin at a conserved Ser-4 residue. Consistent with the resemblance of the Ser-4 phosphorylation site to the Polo-like kinase 1 (Plk1) consensus recognition sequence, inhibition of Plk1 by a...

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Identifiers

PMID: 15190079
DOI: 10.1074/jbc.M403264200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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B23/nucleophosmin serine 4 phosphorylation mediates mitotic functions of polo-like kinase 1.PMID 15190079Read ↗

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