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Article

CHK1 phosphorylates CDC25B during the cell cycle in the absence of DNA damage.

Journal of cell science - 15 Oct 2006

Schmitt Estelle, Boutros Rose, Froment Carine, Monsarrat Bernard, Ducommun Bernard, Dozier Christine

Abstract excerpt

CDC25B is one of the three human phosphatases that activate the CDK-cyclin complexes, thereby triggering cell-cycle progression and division. Commitment to early mitotic events depends on the activation of a centrosomal pool of CDK1-cyclin-B1, and CDC25B is thought to be involved in initiating this centrosomal CDK1-cyclin-B1 activity. Centrosome-associated checkpoint kinase 1 (CHK1) has been proposed to...

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Identifiers

PMID: 17003105
DOI: 10.1242/jcs.03200

Genes

CDK1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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CHK1 phosphorylates CDC25B during the cell cycle in the absence of DNA damage.PMID 17003105Read ↗

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