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Article

Nucleophosmin/B23 is a target of CDK2/cyclin E in centrosome duplication.

Cell - 29 Sept 2000

Okuda M, Horn H F, Tarapore P, Tokuyama Y, Smulian A G, Chan P K, Knudsen E S, Hofmann I A, Snyder J D, Bove K E, Fukasawa K

Abstract excerpt

In animal cells, duplication of centrosomes and DNA is coordinated. Since CDK2/cyclin E triggers initiation of both events, activation of CDK2/cyclin E is thought to link these two events. We identified nucleophosmin (NPM/B23) as a substrate of CDK2/cyclin E in centrosome duplication. NPM/B23 ass...

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Source

Identifiers

PMID: 11051553
DOI: 10.1016/s0092-8674(00)00093-3

Genes

CDK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-11051553-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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