Article
Sleep and COMT polymorphism in ADHD children: preliminary actigraphic data.
Journal of the American Academy of Child and Adolescent Psychiatry - 1 Aug 2006
Gruber Reut, Grizenko Natalie, Schwartz George, Ben Amor Leila, Gauthier Julie, de Guzman Rosherrie, Joober Ridha
Abstract excerpt
OBJECTIVE: To examine whether COMT (catechol-O-methyltransferase) polymorphism modulates aspects of sleep in children diagnosed with attention-deficit/hyperactivity disorder (ADHD). METHOD: Nightly sleep actigraphic recordings during a double-blind, placebo-controlled, crossover clinical study (1 week of 0.5 mg/kg MPH; 1 week of placebo) were obtained for 34 children, 7.4 to 12 years old, diagnosed with ADHD...
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