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Article

COMT Val108/158Met polymorphism and the modulation of task-oriented behavior in children with ADHD.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Dec 2008

Sengupta Sarojini, Grizenko Natalie, Schmitz Norbert, Schwartz George, Bellingham Johanne, Polotskaia Anna, Stepanian Marina Ter, Goto Yukiori, Grace Anthony A, Joober Ridha

Abstract excerpt

It has been suggested that the symptoms of attention-deficit/hyperactivity disorder (ADHD), including inattention and/or hyperactivity/impulsivity, translate into deficits in task-oriented behavior or problem-focused activity. The frontosubcortical dopamine pathway has been implicated in ADHD. On...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 18580877
DOI: 10.1038/npp.2008.85
PMCID: PMC2885152

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18580877-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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COMT Val108/158Met polymorphism and the modulation of task-oriented behavior in children with ADHD.PMID 18580877Read ↗

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The methionine allele of the COMT polymorphism impairs prefrontal cognition in children and adolescents with ADHD.Semantic proximity Read ↗

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