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Article

Dopamine transporter genotype influences the physiological response to medication in ADHD.

Brain : a journal of neurology - 1 Aug 2006

Gilbert Donald L, Wang Zhewu, Sallee Floyd R, Ridel Keith R, Merhar Stephanie, Zhang Jie, Lipps Tara D, White Colin, Badreldin Nevert, Wassermann Eric M

Abstract excerpt

Attention deficit hyperactivity disorder (ADHD) is a complex, multifactorial disorder characterized by physical hyperactivity and behavioural disinhibition. Short interval cortical inhibition (SICI), measured in motor cortex with transcranial magnetic stimulation, is reduced in ADHD and correlates with symptom severity. However, ADHD medication-induced changes in SICI vary widely among normal individuals and have...

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Identifiers

PMID: 16760197
DOI: 10.1093/brain/awl147

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