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Article

Genetic changes during mouse skin tumorigenesis.

Environmental health perspectives - 1 Jun 1991

Burns P A, Bremner R, Balmain A

Abstract excerpt

This paper describes specific genetic changes involving chromosome 7 in mouse skin tumors, the most important consequence of which appears to be an alteration in the allelic balance of normal and mutant H-ras genes. The use of restriction-fragment-length polymorphisms in F1 hybrid mice demonstrates that trisomy of chromosome 7 is an early event preceding papilloma formation, and further events, such as mitotic...

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Share to Alleles
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Genes, Tumor Suppressor

Share to Polymorphism, Restriction Fragment Length

Share to Recombination, Genetic

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Identifiers

PMID: 1685445
DOI: 10.1289/ehp.919341
PMCID: PMC1568051

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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