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Article

Overlapping loss of heterozygosity by mitotic recombination on mouse chromosome 7F1-ter in skin carcinogenesis.

Proceedings of the National Academy of Sciences of the United States of America - 1 Sept 1991

Bianchi A B, Navone N M, Aldaz C M, Conti C J

Abstract excerpt

A significant role for mouse chromosome 7 abnormalities during chemically induced skin carcinogenesis has been advanced based on previous cytogenetic and molecular studies. To determine the frequency of allelic losses at different loci of chromosome 7 in skin tumors induced in the outbred SENCAR mouse stock by a two-stage initiation-promotion protocol, we compared the constitutional and tumor genotypes of...

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Identifiers

PMID: 1909026
DOI: 10.1073/pnas.88.17.7590
PMCID: PMC52347

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