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Article

Functional loss of tumour suppressor genes in multistage chemical carcinogenesis.

Princess Takamatsu symposia - 1 Jan 1991

Balmain A, Kemp C J, Burns P A, Stoler A B, Fowlis D J, Akhurst R J

Abstract excerpt

Studies of multistage carcinogenesis in mouse skin have provided many of the early concepts of tumour initiation, promotion and progression. Genetic approaches have led to the identification of a number of mutational alterations in proto-oncogenes and tumour suppressor genes which take place at s...

Topics

Animals
Carcinoma
Carcinoma, Squamous Cell
Cell Transformation, Neoplastic
Genes, Tumor Suppressor
Genes, ras
Humans
Mice
Mutation
Proto-Oncogene Mas
Skin Neoplasms
Transforming Growth Factor beta

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 1844254

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1844254-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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