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Article

Induction of different genetic changes by different classes of chemical carcinogens during progression of mouse skin tumors.

Molecular carcinogenesis - 1 Oct 1994

Bremner R, Kemp C J, Balmain A

Abstract excerpt

By analysis of skin tumors from F1 hybrid mice we demonstrated that the genetic events that occur during tumor progression depend on the type of chemical carcinogenesis protocol used to induce tumor growth. More than 95% of tumors induced by initiation with 7,12-dimethylbenz[a]anthracene (DMBA) and promotion with 12-O-tetradecanoyl-phorbol-13-acetate (TPA) exhibited mutations in Ha-ras and trisomy of chromosome...

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Source

Identifiers

PMID: 7916997
DOI: 10.1002/mc.2940110206

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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