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Article

NOS2A and the modulating effect of cigarette smoking in Parkinson's disease.

Annals of neurology - 1 Sept 2006

Hancock Dana B, Martin Eden R, Fujiwara Kenichiro, Stacy Mark A, Scott Burton L, Stajich Jeffrey M, Jewett Rita, Li Yi-Ju, Hauser Michael A, Vance Jeffery M, Scott William K

Abstract excerpt

OBJECTIVE: Inducible nitric oxide synthase, a protein product of NOS2A, generates nitric oxide as a defense mechanism, but excessive levels threaten cellular survival. NOS2A is a candidate gene for Parkinson's disease (PD) that potentially interacts with cigarette smoking. We examined NOS2A for association with PD risk and age at onset (AAO) and for interaction with smoking. METHODS: We genotyped 13 NOS2A single...

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Identifiers

PMID: 16823855
DOI: 10.1002/ana.20915

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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