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Article

Smoking and Parkinson disease: Evidence for gene-by-smoking interactions.

Neurology - 13 Feb 2018

Lee Pei-Chen, Ahmed Ismaïl, Loriot Marie-Anne, Mulot Claire, Paul Kimberly C, Bronstein Jeff M, Ritz Beate, Elbaz Alexis

Abstract excerpt

OBJECTIVE: To investigate whether cigarette smoking interacts with genes involved in individual susceptibility to xenobiotics for the risk of Parkinson disease (PD). METHODS: Two French population-based case-control studies (513 patients, 1,147 controls) were included as a discovery sample to examine gene-smoking interactions based on 3,179 single nucleotide polymorphisms (SNPs) in 289 genes involved in...

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Identifiers

PMID: 29352099
DOI: 10.1212/WNL.0000000000004953
PMCID: PMC5818012

Genes

RXRA

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