Article
Nitric oxide synthase genes and their interactions with environmental factors in Parkinson's disease.
Neurogenetics - 1 Oct 2008
Hancock Dana B, Martin Eden R, Vance Jeffery M, Scott William K
Abstract excerpt
Nitric oxide synthase (NOS) genes (NOS1, NOS2A, and NOS3) may create excess nitric oxide that contributes to neurodegeneration in Parkinson's disease (PD). NOS genes might also interact with one another or with environmental factors in PD. Coding and tagging single nucleotide polymorphisms (SNPs) (27 NOS1, 18 NOS2A, and five NOS3 SNPs) were genotyped in families with PD (1,065 cases and 1,180 relative and other...
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