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Article

Analysis of single nucleotide polymorphisms in the NOS2A gene and interaction with smoking in age-related macular degeneration.

Annals of human genetics - 1 May 2010

Ayala-Haedo Juan A, Gallins Paul J, Whitehead Patrice L, Schwartz Stephen G, Kovach Jaclyn L, Postel Eric A, Agarwal Anita, Wang Gaofeng, Haines Jonathan L, Pericak-Vance Margaret A, Scott William K

Abstract excerpt

Age-related macular degeneration (AMD) is a complex degenerative retinal disease influenced by both genetic and environmental risk factors. We assessed whether single nucleotide polymorphisms (SNPs) in the NOS2A gene increase risk and modulate the effect of smoking in AMD. 998 Caucasian subjects...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20374233
DOI: 10.1111/j.1469-1809.2010.00570.x
PMCID: PMC2882995

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20374233-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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