PARK16 polymorphisms, interaction with smoking, and sporadic Parkinson's disease in Japan.

doi:10.1016/j.jns.2016.01.021

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Article

PARK16 polymorphisms, interaction with smoking, and sporadic Parkinson's disease in Japan.

Journal of the neurological sciences - 15 Mar 2016

Miyake Yoshihiro, Tanaka Keiko, Fukushima Wakaba, Kiyohara Chikako, Sasaki Satoshi, Tsuboi Yoshio, Oeda Tomoko, Shimada Hiroyuki, Kawamura Nobutoshi, Sakae Nobutaka, Fukuyama Hidenao, Hirota Yoshio, Nagai Masaki, Nakamura Yoshikazu

Abstract excerpt

Epidemiological evidence on the relationships between PARK16 single nucleotide polymorphisms (SNPs) and Parkinson's disease (PD) is inconsistent. We examined this issue in Japan. Included were 229 cases within six years of PD onset. Controls were 356 patients without neurodegenerative disease. Compared with subjects with the AA genotype of SNP rs823128, those with the AG genotype, but not the GG genotype, had a...

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PMID: 26944116
DOI: 10.1016/j.jns.2016.01.021

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