Article
Comprehensive association analysis of the NOS2A gene with Parkinson disease.
Neurology - 12 Dec 2006
Schulte C, Sharma M, Mueller J C, Lichtner P, Prestel J, Berg D, Gasser T
Abstract excerpt
Inducible nitric oxide synthase (NOS2A) may be involved in the oxidative stress pathology of Parkinson disease (PD). Two previous studies reported an association of a single nucleotide polymorphism (rs1060826) with PD. A replication study of 340 German patients and 680 controls showed no significant association between 12 genotyped polymorphisms and PD. NOS2A is therefore not a major susceptibility locus in our...
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