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Article

A Genome-wide study on the genetic and causal effects of smoking in neurodegeneration.

Journal of translational medicine - 4 Jul 2025

Chen Chaochao, Zhu Shouqiang, Zheng Zhiying, Ding Xiahao, Shi Weihai, Xia Tianjiao, Gu Xiaoping

Abstract excerpt

BACKGROUND: Smoking represents the largest preventable risk factor for human health, yet previous studies have failed to establish conclusive evidence regarding the causal relationship between smoking and neurodegenerative diseases. This study employs genetic correlation and Mendelian randomization analyses to investigate the potential association between smoking and neurodegenerative disorders. METHODS: This...

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Identifiers

PMID: 40615926
DOI: 10.1186/s12967-025-06688-9
PMCID: PMC12228318

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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