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Article

CFH gene variant, Y402H, and smoking, body mass index, environmental associations with advanced age-related macular degeneration.

Human heredity - 1 Jan 2006

Seddon Johanna M, George Sarah, Rosner Bernard, Klein Michael L

Abstract excerpt

OBJECTIVES: We tested the hypothesis that modifiable lifestyle factors alter the genetic susceptibility associated with a common coding variant in the complement factor H (CFH) gene, Y402H, for the leading cause of blindness among the elderly, age-related macular degeneration (AMD). METHODS: In this case-control association analysis, Caucasian participants in the multicenter Age-Related Eye Disease Study with...

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Source

Identifiers

PMID: 16816528
DOI: 10.1159/000094141

Genes

CFH

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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