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Article

Systematic review and meta-analysis of the association between complement factor H Y402H polymorphisms and age-related macular degeneration.

Human molecular genetics - 15 Sept 2006

Thakkinstian Ammarin, Han Pearline, McEvoy Mark, Smith Wayne, Hoh Josephine, Magnusson Kristinn, Zhang Kang, Attia John

Abstract excerpt

Age-related macular degeneration (AMD) is the leading cause of blindness in the developed world and complement factor H (CFH) polymorphism has been found to associated with the AMD. We performed a meta-analysis to estimate the magnitude of the gene effect and the possible mode of action. A meta-analysis of eight studies assessing association between the CFH Y402H polymorphism and AMD was performed. Data...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16905558
DOI: 10.1093/hmg/ddl220

Genes

CFH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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