Coding and noncoding variants in the CFH gene and cigarette smoking influence the risk of age-related macular degeneration in a Japanese population.

doi:10.1167/iovs.07-0426

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Article

Coding and noncoding variants in the CFH gene and cigarette smoking influence the risk of age-related macular degeneration in a Japanese population.

Investigative ophthalmology & visual science - 1 Nov 2007

Mori Keisuke, Gehlbach Peter L, Kabasawa Sho, Kawasaki Izumi, Oosaki Masataka, Iizuka Hiroyuki, Katayama Shigehiro, Awata Takuya, Yoneya Shin

Abstract excerpt

PURPOSE: Ethnic variation has been reported in age-related macular degeneration (AMD)-associated Y402H polymorphism in complement factor H (CFH). This variation is evident in the Japanese population. Recently a strong association between a novel single-nucleotide polymorphism (SNP; rs1410996) in the CFH gene and AMD has been identified in Caucasian patients. The present study was undertaken to investigate whether...

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PMID: 17962488
DOI: 10.1167/iovs.07-0426

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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