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Article

Assessing susceptibility to age-related macular degeneration with genetic markers and environmental factors.

Archives of ophthalmology (Chicago, Ill. : 1960) - 1 Mar 2011

Chen Yuhong, Zeng Jiexi, Zhao Chao, Wang Kevin, Trood Elizabeth, Buehler Jeanette, Weed Matthew, Kasuga Daniel, Bernstein Paul S, Hughes Guy, Fu Victoria, Chin Jessica, Lee Clara, Crocker Maureen, Bedell Matthew, Salasar Francesca, Yang Zhenglin, Goldbaum Michael, Ferreyra Henry, Freeman William R, Kozak Igor, Zhang Kang

Abstract excerpt

OBJECTIVES: To evaluate the independent and joint effects of genetic factors and environmental variables on advanced forms of age-related macular degeneration (AMD), including geographic atrophy and choroidal neovascularization, and to develop a predictive model with genetic and environmental factors included. METHODS: Demographic information, including age at onset, smoking status, and body mass index, was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21402993
DOI: 10.1001/archophthalmol.2011.10
PMCID: PMC4134685

Genes

CFH
HTRA1
CFB

Provenance

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