Article
Association of complement factor H gene polymorphisms with age-related macular egeneration susceptibility.
International journal of clinical and experimental pathology - 1 Jan 2015
Hao Xiao-Feng, Xie Li-Ke, Tang You-Zhi, Xie Wan-Kun, Zhang Zhi-Fang, Qi Yi-Xin, Xiao Wen-Zheng, Zhang Jing
Abstract excerpt
OBJECTIVE: This study was aimed to confirm whether I62V and Y402H polymorphisms of complement factor H (CFH) were risk factors for age-related macular degeneration (AMD). METHOD: 109 AMD patients and 165 AMD-free controls were enrolled in the study. The I62V and Y402H polymorphisms were analyzed by polymerase chain reaction-restriction fragment length of polymorphism (PCR-RFLP). Odds ratios (ORs) with 95%...
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