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Article

A prospective study of 2 major age-related macular degeneration susceptibility alleles and interactions with modifiable risk factors.

Archives of ophthalmology (Chicago, Ill. : 1960) - 1 Jan 2007

Schaumberg Debra A, Hankinson Susan E, Guo Qun, Rimm Eric, Hunter David J

Abstract excerpt

OBJECTIVES: To delineate the magnitude of susceptibility to age-related macular degeneration (AMD) due to common variants in the gene for complement factor H (CFH) and the predicted gene LOC387715 and to determine whether these variants interact with modifiable risk factors. METHODS: We compared cases who developed AMD (n = 457) with 1071 age- and sex-matched control subjects in a prospective nested case-control...

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Identifiers

PMID: 17210852
DOI: 10.1001/archopht.125.1.55

Genes

CFH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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