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Article

Associations between COMTVal158Met polymorphism and cognition: direct or indirect effects?

European psychiatry : the journal of the Association of European Psychiatrists - 1 Jul 2006

Krabbendam Lydia, Isusi Pilar, Galdos Paloma, Echevarria Elena, Bilbao José Ramón, Martin-Pagola Ainhoa, Papiol Sergi, Castaño Luis, Van Os Jim

Abstract excerpt

BACKGROUND: Previous work suggests that reaction time variability (RTV) in attentional tasks, as a measure of cognitive stability, is associated with degree of Val loading in COMT Val(158)Met genotype, and that this association may be relevant for the aetiology of schizophrenia. This study examined (i) to what degree RTV pertaining to tasks of varying cognitive complexity would be associated with increased risk...

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Source

Identifiers

PMID: 16815691
DOI: 10.1016/j.eurpsy.2006.03.007

Genes

COMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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