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Article

Putative role of the COMT gene polymorphism (Val158Met) on verbal working memory functioning in a healthy population.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Sept 2008

Aguilera M, Barrantes-Vidal N, Arias B, Moya J, Villa H, Ibáñez M I, Ruipérez M A, Ortet G, Fañanás L

Abstract excerpt

Working memory has been described as a neurocognitive probe of prefrontal brain functioning. Genetic variability related with catechol-O-methyltransferase (COMT) gene (Val158Met polymorphism) has received increasing attention as a possible modulator of working memory tasks in both schizophrenic patients and healthy subjects, although inconsistencies across studies have been found. This may be related to the...

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Identifiers

PMID: 18213617
DOI: 10.1002/ajmg.b.30705

Genes

COMT

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Putative role of the COMT gene polymorphism (Val158Met) on verbal working memory functioning in a healthy population.PMID 18213617Read ↗

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Catechol-O-methyltransferase (COMT) polymorphisms modulate working memory in individuals with schizophrenia and healthy controls.Semantic proximity Read ↗

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