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Article

Real-time PCR detection of multiple lamivudine-resistant mutations with displacing probes in a single tube.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Apr 2007

Wen Huixin, Li Qingge

Abstract excerpt

BACKGROUND: Detection of lamivudine-resistant hepatitis B virus (HBV) is essential to clinical diagnosis and treatment. OBJECTIVES: To establish a single tube, real-time PCR assay for simultaneous detection of multiple lamivudine-resistant mutations in serum samples. STUDY DESIGN: By using four sequence-specific displacing probes labeled with different fluorophores, a single real-time PCR reaction can tell...

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Source

Identifiers

PMID: 17329165
DOI: 10.1016/j.jcv.2007.01.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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