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Article

[FLT3 gene mutation and its prognostic implication in patients with acute leukemia.].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 1 Jan 2010

Abstract excerpt

OBJECTIVE: To evaluate the prevalence of FLT3 mutation in different subtypes of acute leukemia (AL) patients diagnosed by WHO criteria and its significance in prognosis. METHODS: Polymerase chain reaction (PCR) was used to detect internal tandem duplication of FLT3 gene (FLT3-ITD) and D835 mutation in 468 firstly diagnosed AL patients and analyzed their prognosis by Kaplan-Meier and log-rank test. RESULTS: In 468...

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Identifiers

PMID: 20302766

Genes

FLT3

Provenance

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