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Article

The association of CTLA-4 and HLA class II autoimmune risk genotype with regulatory T cell marker expression in 5-year-old children.

Clinical and experimental immunology - 1 Jul 2006

Jonson C-O, Hedman M, Karlsson Faresjö M, Casas R, Ilonen J, Ludvigsson J, Vaarala O

Abstract excerpt

Regulatory T cells (Treg) are involved in the maintenance of peripheral tolerance by suppression of autoreactive lymphocytes that have avoided thymic depletion. The defective function of Treg cells has recently attracted attention in autoimmune diseases such as type 1 diabetes (T1D), rheumatoid arthritis and multiple sclerosis. Susceptibility to these diseases is associated with specific human leucocyte antigen...

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Topics

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Share to Antigens, Differentiation
Share to Cell Separation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CTLA-4 Antigen

Share to Genes, MHC Class II

Share to Receptors, Interleukin-2

Share to Staining and Labeling

Share to Statistics, Nonparametric

Share to T-Lymphocytes, Regulatory

Source

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Identifiers

PMID: 16792673
DOI: 10.1111/j.1365-2249.2006.03106.x
PMCID: PMC1942013

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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