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Article

Association of cytotoxic T lymphocyte antigen-4 gene polymorphisms and HLA class II alleles with the development of type 1 diabetes in Korean children and adolescents.

Journal of Korean medical science - 1 Dec 2009

Jung Min Ho, Yu Jeesuk, Shin Choong Ho, Suh Byung Kyu, Yang Sei Won, Lee Byung Churl

Abstract excerpt

We studied the association of cytotoxic T lymphocyte antigen-4 gene (CTLA4) polymorphisms with the development of type 1 diabetes (T1D) in Korean children and adolescents. A total of 176 Korean subjects (92 females and 84 males) with childhood-onset T1D were studied. The A/G polymorphism at position 49 in CTLA4 exon 1 and the C/T polymorphism at position -318 in the CTLA4 promoter were analyzed by PCR-RFLP...

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Share to Antigens, CD
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Child, Preschool

Share to CTLA-4 Antigen

Share to Diabetes Mellitus, Type 1

Share to Histocompatibility Antigens Class II

Share to Polymorphism, Genetic

Source

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Identifiers

PMID: 19949652
DOI: 10.3346/jkms.2009.24.6.1004
PMCID: PMC2775844

Genes

CTLA4

Variants

Provenance

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