Article
CTLA4 is differentially associated with autoimmune diseases in the Dutch population.
Human genetics - 1 Oct 2005
Zhernakova Alexandra, Eerligh Peter, Barrera Pilar, Wesoly Joanna Z, Weseloy Joanna Z, Huizinga Tom W J, Roep Bart O, Wijmenga Cisca, Koeleman Bobby P C
Abstract excerpt
Cytotoxic T lymphocyte-associated antigen 4 (CTLA4) is an important negative regulator of T-cell response and its genetic association with type 1 diabetes (T1D) has recently been demonstrated. The frequent co-association of autoimmune diseases (AID) and the implication from multiple genome scans...
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