Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Immune regulatory T cells in siblings of children suffering from type 1 diabetes mellitus.

Scandinavian journal of immunology - 1 Nov 2006

Michalek J, Vrabelova Z, Hrotekova Z, Kyr M, Pejchlova M, Kolouskova S, Faresjö M, Stechova K

Abstract excerpt

Patients with type 1 diabetes are suffering from defects in immune regulatory cells. Their siblings may be at increased risk of type 1 diabetes especially if they are carriers of certain human leucocyte antigen (HLA) alleles. In a prospective non-randomized study, we intended to evaluate 31 healthy siblings of paediatric patients with type 1 diabetes and explore immune regulatory populations of CD4+CD25+ T cells...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autoantibodies
Share to CD4-Positive T-Lymphocytes

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 1

Share to HLA Antigens

Share to Infant

Share to Killer Cells, Natural

Share to Siblings

Share to T-Lymphocytes, Regulatory

Source

Identifiers

PMID: 17032246
DOI: 10.1111/j.1365-3083.2006.01837.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Immune regulatory T cells in siblings of children suffering from type 1 diabetes mellitus.PMID 17032246Read ↗

T-Regulatory Cell Subsets in Children with Type 1 Diabetes Mellitus: Relation to Control of the Disease.Semantic proximity Read ↗

The association of CTLA-4 and HLA class II autoimmune risk genotype with regulatory T cell marker expression in 5-year-old children.Semantic proximity Read ↗

Extension of the CD4⁺Foxp3⁺CD25(-/low) regulatory T-cell subpopulation in type 1 diabetes mellitus.Semantic proximity Read ↗

Defective HLA class II expression in monocytes of type 1 diabetic patients. The Childhood Diabetes in Finland Study Group.Semantic proximity Read ↗

Decreased CD127 expression on CD4+ T-cells and elevated frequencies of CD4+CD25+CD127- T-cells in children with long-lasting type 1 diabetes.Semantic proximity Read ↗

Down syndrome, autoimmunity and T regulatory cells.Semantic proximity Read ↗

[Genetic and immunologic risks for development of type 1 diabetes--experiences from an intervention trial].Semantic proximity Read ↗

Immune activation and T cell subset abnormalities in circulation of patients with recently diagnosed type I diabetes mellitus.Semantic proximity Read ↗

Administration of CD4+CD25highCD127− Regulatory T Cells Preserves β-Cell Function in Type 1 Diabetes in ChildrenSemantic proximity Read ↗

Autologous Regulatory T Cells for the Treatment of Type 1 DiabetesSemantic proximity Read ↗

CD25 expression on donor CD4+ or CD8+ T cells is associated with an increased risk for graft-versus-host disease after HLA-identical stem cell transplantation in humansSemantic proximity Read ↗

The role of regulatory T cell (Treg) subsets in gestational diabetes mellitusSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.