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Article

Structure of stem-loop IV of Tetrahymena telomerase RNA.

The EMBO journal - 12 Jul 2006

Chen Yu, Fender Jessica, Legassie Jason D, Jarstfer Michael B, Bryan Tracy M, Varani Gabriele

Abstract excerpt

Conserved domains within the RNA component of telomerase provide the template for reverse transcription, recruit protein components to the holoenzyme and are required for enzymatic activity. Among the functionally essential domains in ciliate telomerase RNA is stem-loop IV, which strongly stimulates telomerase activity and processivity even when provided in trans. The NMR structure of Tetrahymena thermophila...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 16778765
DOI: 10.1038/sj.emboj.7601195
PMCID: PMC1500990

Genes

TERT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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