Article
A new telomerase RNA element that is critical for telomere elongation.
Nucleic acids research - 1 Sept 2013
Laterreur Nancy, Eschbach Sébastien H, Lafontaine Daniel A, Wellinger Raymund J
Abstract excerpt
The stability of chromosome ends, the telomeres, is dependent on the ribonucleoprotein telomerase. In vitro, telomerase requires at least one RNA molecule and a reverse transcriptase-like protein. However, for telomere homeostasis in vivo, additional proteins are required. Telomerase RNAs of different species vary in size and sequence and only few features common to all telomerases are known. Here we show that...
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