Article
Structure and function of telomerase RNA.
Current opinion in structural biology - 1 Jun 2006
Theimer Carla A, Feigon Juli
Abstract excerpt
Maintenance of telomeres by the enzyme telomerase is essential for genomic stability and cell viability in ciliates, vertebrates and yeast. The minimal components of telomerase required for catalytic activity are the telomerase reverse transcriptase (TERT) protein and the template-containing telomerase RNA (TER). Recent studies have afforded significant advances in the biophysical characterization of telomerase...
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