Article
The brain tumor gene negatively regulates neural progenitor cell proliferation in the larval central brain of Drosophila.
Development (Cambridge, England) - 1 Jul 2006
Bello Bruno, Reichert Heinrich, Hirth Frank
Abstract excerpt
Brain development in Drosophila is characterized by two neurogenic periods, one during embryogenesis and a second during larval life. Although much is known about embryonic neurogenesis, little is known about the genetic control of postembryonic brain development. Here we use mosaic analysis with a repressible cell marker (MARCM) to study the role of the brain tumor (brat) gene in neural proliferation control and...
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