Article
dp53 Restrains ectopic neural stem cell formation in the Drosophila brain in a non-apoptotic mechanism involving Archipelago and cyclin E.
PloS one - 1 Jan 2011
Ouyang Yingshi, Song Yan, Lu Bingwei
Abstract excerpt
Accumulating evidence suggests that tumor-initiating stem cells or cancer stem cells (CSCs) possibly originating from normal stem cells may be the root cause of certain malignancies. How stem cell homeostasis is impaired in tumor tissues is not well understood, although certain tumor suppressors have been implicated. In this study, we use the Drosophila neural stem cells (NSCs) called neuroblasts as a model to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
