Article
The prospero gene specifies cell fates in the Drosophila central nervous system.
Cell - 3 May 1991
Doe C Q, Chu-LaGraff Q, Wright D M, Scott M P
Abstract excerpt
The molecular mechanisms used to generate neuronal diversity are largely unknown. To identify genes controlling cell fate in the Drosophila central nervous system, we screened for mutations that alter expression of homeobox genes in the developing central nervous system (indicating changes in cell fates). We also screened "enhancer trap" lines to identify genes expressed in neuronal stem cells (neuroblasts). The...
Topics
- Animals
- Axons
- Blastoderm
- Central Nervous System
- Drosophila
- Ganglia
- Gene Expression Regulation
- Genes
- Genes, Homeobox
- Mutation
- Neural Pathways
- Neuroglia