Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Essential roles of Drosophila RhoA in the regulation of neuroblast proliferation and dendritic but not axonal morphogenesis.

Neuron - 1 Feb 2000

Lee T, Winter C, Marticke S S, Lee A, Luo L

Abstract excerpt

The pleiotropic functions of small GTPase Rho present a challenge to its genetic analysis in multicellular organisms. We report here the use of the MARCM (mosaic analysis with a repressible cell marker) system to analyze the function of RhoA in the developing Drosophila brain. Clones of cells homozygous for null RhoA mutations were specifically labeled in the mushroom body (MB) neurons of mosaic brains. We found...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animal Structures
Share to Antimetabolites
Share to Axons

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Bromodeoxyuridine

Share to Cell Size

Share to Dendrites

Share to rhoA GTP-Binding Protein

Share to Stem Cells

Source

Identifiers

PMID: 10719887
DOI: 10.1016/s0896-6273(00)80896-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Essential roles of Drosophila RhoA in the regulation of neuroblast proliferation and dendritic but not axonal morphogenesis.PMID 10719887Read ↗

Rac GTPases control axon growth, guidance and branching.Semantic proximity Read ↗

Mosaic analysis with a repressible cell marker for studies of gene function in neuronal morphogenesis.Semantic proximity Read ↗

A mosaic genetic screen for genes necessary for Drosophila mushroom body neuronal morphogenesis.Semantic proximity Read ↗

Mosaic analysis reveals a cell-autonomous, neuronal requirement for Commissureless in the Drosophila CNS.Semantic proximity Read ↗

The brain tumor gene negatively regulates neural progenitor cell proliferation in the larval central brain of Drosophila.Semantic proximity Read ↗

Brat is a Miranda cargo protein that promotes neuronal differentiation and inhibits neuroblast self-renewal.Semantic proximity Read ↗

A mosaic genetic screen for novel mutations affecting Drosophila neuroblast divisions.Semantic proximity Read ↗

Characterization of rho GTPase family homologues in Drosophila melanogaster: overexpressing Rho1 in retinal cells causes a late developmental defect.Semantic proximity Read ↗

RABR-1, an atypical Rab-related GTPase, cell-nonautonomously restricts somatosensory dendrite branching.Semantic proximity Read ↗

Miranda directs Prospero to a daughter cell during Drosophila asymmetric divisions.Semantic proximity Read ↗

rhomboid, a gene required for dorsoventral axis establishment and peripheral nervous system development in Drosophila melanogaster.Semantic proximity Read ↗

Rho and Ras GTPases in axon growth, guidance, and branching.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.