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Article

Parsing the genetic heterogeneity of chromosome 12q susceptibility genes for Alzheimer disease by family-based association analysis.

Neurogenetics - 1 Jul 2006

Lin Ping-I, Martin Eden R, Browning-Large Carrie A, Schmechel Donald E, Welsh-Bohmer Kathleen A, Doraiswamy P Murali, Gilbert John R, Haines Jonathan L, Pericak-Vance Margaret A

Abstract excerpt

Previous linkage studies have suggested that chromosome 12 may harbor susceptibility genes for late-onset Alzheimer disease (LOAD). No risk genes on chromosome 12 have been conclusively identified yet. We have reported that the linkage evidence for LOAD in a 12q region was significantly increased in autopsy-confirmed families particularly for those showing no linkage to alpha-T catenin gene, a LOAD candidate gene...

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Share to Alzheimer Disease
Share to Chromosomes, Human, Pair 12

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Linkage Disequilibrium

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 16770605
DOI: 10.1007/s10048-006-0047-z

Genes

ATF7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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