Article
Identification of novel genes in late-onset Alzheimer's disease.
Experimental gerontology - 1 Dec 2000
Pericak-Vance M A, Grubber J, Bailey L R, Hedges D, West S, Santoro L, Kemmerer B, Hall J L, Saunders A M, Roses A D, Small G W, Scott W K, Conneally P M, Vance J M, Haines J L
Abstract excerpt
Four genes affecting Alzheimer's Disease (AD)(AP, PS1, PS2, and APOE) have been identified and a fifth potential gene localized to chromosome 12. Collectively, these genes explain at most half of the genetic effect in AD. Understanding the genetics of AD is critical to developing new treatments....
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