Article

Evaluation of gene-based family-based methods to detect novel genes associated with familial late onset Alzheimer disease

2018-01-08

Abstract excerpt

Gene-based tests to study the combined effect of rare variants towards a particular phenotype have been widely developed for case-control studies, but their evolution and adaptation for family-based studies, especially for complex incomplete families, has been slower. In this study, we have performed a practical examination of all the latest gene-based methods available for family-based study designs using both si...

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Literature Corpus work: 2507f816-f6cd-5fc2-85d2-02638d5317f7
DOI: 10.1101/242545

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