Article
Identification of clustered YY1 binding sites in imprinting control regions.
Genome research - 1 Jul 2006
Kim Jeong Do, Hinz Angela K, Bergmann Anne, Huang Jennifer M, Ovcharenko Ivan, Stubbs Lisa, Kim Joomyeong
Abstract excerpt
Mammalian genomic imprinting is regulated by imprinting control regions (ICRs) that are usually associated with tandem arrays of transcription factor binding sites. In this study, the sequence features derived from a tandem array of YY1 binding sites of Peg3-DMR (differentially methylated region) led us to identify three additional clustered YY1 binding sites, which are also localized within the DMRs of Xist,...
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