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Article

Regulation of the imprinted Dlk1-Dio3 locus by allele-specific enhancer activity.

Genes & development - 1 Jan 2016

Luo Zhuojuan, Lin Chengqi, Woodfin Ashley R, Bartom Elizabeth T, Gao Xin, Smith Edwin R, Shilatifard Ali

Abstract excerpt

Genomic imprinting is a critical developmental process characteristic of parent of origin-specific gene expression. It is well accepted that differentially DNA-methylated regions (DMRs) and enhancers are two major classes of cis-elements determining parent of origin-specific gene expression, with each recruiting different sets of transcription factors. Previously, we identified the AF4/FMR2 (AFF) family protein...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26728555
DOI: 10.1101/gad.270413.115
PMCID: PMC4701981

Genes

AFF3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Regulation of the imprinted Dlk1-Dio3 locus by allele-specific enhancer activity.PMID 26728555Read ↗

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