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Article

Identification of an Evolutionarily Conserved Cis-Regulatory Element Controlling the Peg3 Imprinted Domain

10 Sept 2013

Abstract excerpt

The mammalian Peg3 domain harbors more than 20 evolutionarily conserved regions (ECRs) that are spread over the 250-kb genomic interval. The majority of these ECRs are marked with two histone modifications, H3K4me1 and H3K27ac, suggesting potential roles as distant regulatory elements for the transcription of the nearby imprinted genes. In the current study, the chromatin conformation capture (3C) method was...

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PMID: 24040411
DOI: 10.1371/journal.pone.0075417

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Identification of an Evolutionarily Conserved Cis-Regulatory Element Controlling the Peg3 Imprinted DomainPMID 24040411Read ↗

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