Article
An intronic DNA sequence within the mouse Neuronatin gene exhibits biochemical characteristics of an ICR and acts as a transcriptional activator in Drosophila.
Mechanisms of development - 1 Jan 2000
Sowpati Divya Tej, Thiagarajan Devi, Sharma Sudhish, Sultana Hina, John Rosalind, Surani Azim, Mishra Rakesh Kumar, Khosla Sanjeev
Abstract excerpt
Imprinting control regions (ICRs) are domains within imprinted loci that are essential for their establishment and maintenance. Imprinted loci can extend over several megabases, encompass both maternally and paternally-expressed genes and exhibit multiple and complex epigenetic modifications including large regions of allele-specific DNA methylation. Differential chromatin organisation has also been observed...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
