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Article

YY1 binding association with sex-biased transcription revealed through X-linked transcript levels and allelic binding analyses.

Scientific reports - 18 Nov 2016

Chen Chih-Yu, Shi Wenqiang, Balaton Bradley P, Matthews Allison M, Li Yifeng, Arenillas David J, Mathelier Anthony, Itoh Masayoshi, Kawaji Hideya, Lassmann Timo, Hayashizaki Yoshihide, Carninci Piero, Forrest Alistair R R, Brown Carolyn J, Wasserman Wyeth W

Abstract excerpt

Sex differences in susceptibility and progression have been reported in numerous diseases. Female cells have two copies of the X chromosome with X-chromosome inactivation imparting mono-allelic gene silencing for dosage compensation. However, a subset of genes, named escapees, escape silencing and are transcribed bi-allelically resulting in sexual dimorphism. Here we conducted in silico analyses of the sexes...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, X-Linked

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Source

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Identifiers

PMID: 27857184
DOI: 10.1038/srep37324
PMCID: PMC5114649

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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