Article

Along the Bos Taurus genome, uncover candidate Imprinting Control Regions

2021-12-28

Abstract excerpt

<h4>ABSTRACT</h4> In mammals, Imprinting Control Regions (ICRs) regulate a subset of genes in a parent-of-origin-specific manner. In both human and mouse, previous studies identified a set of CpG-rich motifs that occurred as clusters in ICRs and germline Differentially Methylated Regions (gDMRs). These motifs consist of the ZFP57 binding site (ZFBS) overlapping a subset of MLL binding units known as MLL morphemes...

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Literature Corpus work: 33e38c25-f15f-5fb0-8e1b-b77a5ec60bf4
DOI: 10.1101/2021.12.27.474271

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