Article
YY1's role in the Peg3 imprinted domain.
Scientific reports - 25 Jul 2017
He Hongzhi, Ye An, Perera Bambarendage P U, Kim Joomyeong
Abstract excerpt
The ICR (Imprinting Control Region) of the Peg3 (Paternally Expressed Gene 3) domain contains an unusual cluster of YY1 binding sites. In the current study, these YY1 binding sites were mutated to characterize the unknown roles in the mouse Peg3 domain. According to the results, paternal and maternal transmission of the mutant allele did not cause any major effect on the survival of the pups. In the mutants, the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
