Article
Molecular genetic alterations of FHIT and p53 genes in benign and malignant thyroid gland lesions.
Mutation research - 25 Jul 2006
Pavelić Kresimir, Dedivitis Rogerio A, Kapitanović Sanja, Cacev Tamara, Guirado Cristiano R, Danić Davor, Radosević Senka, Brkić Kornelije, Pegan Boris, Krizanac Simun, Kusić Zvonko, Spaventi Sime, Bura Miljenko
Abstract excerpt
Several oncogenes and tumor-suppressor genes are involved either as early or late event in thyroid gland carcinogenesis. Human FHIT (fragile histidine triad) gene is highly conserved gene whose loss of function may be important in the development and/or progression of various types of cancer. We...
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