Article
Mutation and abnormal expression of the fragile histidine triad gene in nasopharyngeal carcinoma.
The Laryngoscope - 1 Sept 2001
Deng Y F, Tian F, Lu Y D, Chen Z C, Xie D H, Yang X M, Shao X Y
Abstract excerpt
OBJECTIVE: To determine alterations of fragile histidine triad (FHIT) gene in nasopharyngeal carcinoma and the correlation of FHIT gene with nasopharyngeal carcinogenesis. STUDY DESIGN: Prospective study. METHODS: A total of 28 nasopharyngeal carcinoma and 16 normal nasopharyngeal epithelium specimens were examined for abnormalities of FHIT gene by nested reverse-transcriptase-polymerase chain reaction and DNA...
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